Klinefelter's Syndrome Facts

• Klinefelter's Syndrome occurs in about 1 out of 500 – 1000 males.
• Small undeveloped testicles are present in all KS men.
• There is a slight increase in risk of KS in pregnancies after the age of 35.
• In Australia approximately 60% of males with KS are undiagnosed.
• KS is the most common cause of male hypogonadism.
• Treatment for KS is the prescribing of androgen replacement therapy starting at adolescence.
• Treatment is life-long.

Possible complications include:

• Attention deficient hyperactivity disorder.
• Autoimmune disorders such as lupus, rheumatoid arthritis, and Sjogren syndrome.
• Breast cancer in men.
• Depression.
• Learning disabilities, including dyslexia, which affects reading.
• A rare type of tumor called an extragonadal germ cell tumor.
• Lung disease.
• Osteoporosis.
• Varicose veins.